'A virus is bad news wrapped up in proteins' Sir Peter Medawar.
Viral RNA is 'at the heart' of virus infection and, therefore, the interactions that it establishes with the host cells are critical for the viral life cycle. Our goal is to uncover the molecular mechanisms underpinning these poorly characterized host-virus interactions and explore their therapeutic potential.
The Castello lab is funded by the vRNP-capture ERC Consolidator grant to discover the viral and cellular proteins that engage with viral RNAs in infected cells. Our data suggest that viruses from different families hijack a highly overlapping set of cellular RNA-binding proteins that play central roles in the viral life cycle. This opens
The Castello lab is funded by the vRNP-capture ERC Consolidator grant to discover the viral and cellular proteins that engage with viral RNAs in infected cells. Our data suggest that viruses from different families hijack a highly overlapping set of cellular RNA-binding proteins that play central roles in the viral life cycle. This opens the possibility to identify host targets for broad spectrum antiviral therapies.
If you are interested in joining the Castellolab as PhD student, you should consider applying to the MRC CVR PhD programme and and the Welcome Trust Integrative infection biology. Deadlines are approaching.
ADVICE:
Write a strong and convincing cover letter explaining why you meet the goals of the programme and why you are a competitive ca
If you are interested in joining the Castellolab as PhD student, you should consider applying to the MRC CVR PhD programme and and the Welcome Trust Integrative infection biology. Deadlines are approaching.
ADVICE:
Write a strong and convincing cover letter explaining why you meet the goals of the programme and why you are a competitive candidate. Highlight your academic and scientific achievements.
Our expertise spans multiple disciplines, from molecular virology and cellular biology to OMICS and computational biology
The MRC University of Glasgow Centre for Virus research harbours state-of-the-art infrastructures and facilities, from BSL3 laboratories and insectaries to RNA sequencing and cryo-EM facilities. With a large critical mass in virology ranging from structural and molecular virology to evolution and epidemiology
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