Full publication list here.

Selected publications

System-wide profiling of RNA-binding proteins uncovers key regulators of virus infection. Garcia-Moreno M, Noerenberg M, Ni S, Jarvelin AI, Gonzalez-Almela E, Lenz C, Bach-Pages M, Cox V, Avolio R, Davis T, Hester S, Sohier TJM, Li B, Michalowsky G, Sanz MA, Carrasco L, Ricci EP, Pelechano V, Davis I., Fischer B, Mohammed S,  Castello A*. Mol Cell (2019). In Press.

The small non-coding vault RNA1-1 acts as a riboregulator of autophagy. Horos R, Alleaume A, Kleinendorst R, Tarafder AK, Schwarzl T, Zielonka EM, Adak A, Castello A, Huber W,  Sachse C, Hentze MW. Cell 2019 Feb 21;176(5):1054-1067.e12. doi: 10.1016/j.cell.2019.01.030. Epub 2019 Feb 14.PMID: 30773316

Protein Syndesmos is a novel RNA-binding protein that regulates primary cilia formation. Avolio R, Järvelin AI, Mohammed S, Agliarulo I, Condelli V, Zoppoli P, Calice G, Sarnataro D, Bechara E, Tartaglia GG, Landriscina M, Castello A*, Esposito F*, Matassa DS*. Nucleic Acids Res. 2018 Dec 14;46(22):12067-12086. doi: 10.1093/nar/gky873.

Unconventional RNA-binding proteins step into the virus-host battlefront. Garcia-Moreno M, Jarvelin AI and Castello A*. 2018. WIREs RNA. 2018 Aug 9:e1498. doi: 10.1002/wrna.1498.

A brave new world of RNA-binding proteins. Hentze MW, Castello A, Schwarzl T, Preiss T. Nat Rev Mol Cell Biol. 2018 Jan 17. doi: 10.1038/nrm.2017.130. PMID:29339797

hnRNPK Recruits PCGF3/5-PRC1 to the Xist RNA B-Repeat to Establish Polycomb-Mediated Chromosomal Silencing. Pintacuda G, Wei G, Roustan C, Kirmizitas BA, Solcan N, Cerase A, Castello A, Mohammed S, Moindrot B, Nesterova TB, Brockdorff N. Mol Cell. 2017 Dec 7;68(5):955-969.e10. doi: 10.1016/j.molcel.2017.11.013.

Specific RNP capture with antisense LNA/DNA mixmers. Rogell BM, Fischer B, Rettel M, Krijgsveld J, Castello A, Hentze MW. RNA. 2017 May 5. pii: rna.060798.117. doi: 10.1261/rna.060798.117. PMID: 28476952

Comprehensive Identification of RNA-Binding Domains in Human Cells. Castello A, Fischer B, Frese CK, Horos R, Alleaume AM, Foehr S, Curk T, Krijgsveld J, Hentze MW. Mol Cell. 2016 Aug 18;63(4):696-710. doi: 10.1016/j.molcel.2016.06.029.

The Cardiomyocyte RNA-Binding Proteome: Links to Intermediary Metabolism and Heart Disease. Liao Y, Castello A, Fischer B, Leicht S, Föehr S, Frese CK, Ragan C, Kurscheid S, Pagler E, Yang H, Krijgsveld J, Hentze MW, Preiss T. Cell Rep. 2016 Aug 2;16(5):1456-69. doi: 10.1016/j.celrep.2016.06.084. Epub 2016 Jul 21. PMID: 27452465

Global changes of the RNA-bound proteome during the maternal-to-zygotic transition in Drosophila. Sysoev VO, Fischer B, Frese CK, Gupta I, Krijgsveld J, Hentze MW, Castello A, Ephrussi A. Nat Commun. 2016 Jul 5;7:12128. doi: 10.1038/ncomms12128. PMID: 27378189

The new (dis)order in RNA regulation. Järvelin AI, Noerenberg M, Davis I, Castello A. Cell Commun Signal. 2016 Apr 6;14:9. doi: 10.1186/s12964-016-0132-3. Review. PMID: 27048167

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J, Hentze MW. Cell. 2012 Jun 8;149(6):1393-406. doi: 10.1016/j.cell.2012.04.031