Alfredo Castello Palomares

Dr. Alfredo Castello Palomares
Principal investigator
Department of Biochemistry, University of Oxford
phone: 00441865613296
Tweeter: @Alf_Castello

Most representative publications

Publications: 39               h-index: 20

i10-index: 29                     Citations: 2087

See all publications here.

  • 2017

Identification of RNA-binding domains of RNA-binding proteins in cultured cells on a system-wide scale with RBDmap. Castello A, Frese CK, Fischer B, Järvelin AI, Horos R, Alleaume AM, Foehr S, Curk T, Krijgsveld J, Hentze MW. Nat Protoc. 2017 Dec;12(12):2447-2464. doi: 10.1038/nprot.2017.106. Epub 2017 Nov 2. PMID:  29095441

  • 2016

Comprehensive Identification of RNA-Binding Domains in Human Cells. Alfredo Castello, Bernd Fischer, Christian K. Frese, Rastislav Horos, Anne-Marie Alleaume, Sophia Foehr, Tomaz Curk, Jeroen Krijgsveld, Matthias W. Hentze. Mol Cell. DOI:

The Cardiomyocyte RNA-Binding Proteome: Links to Intermediary Metabolism and Heart Disease. Yalin Liao, Alfredo Castello, Bernd Fischer, Stefan Leicht, Sophia Föehr, Christian K. Frese, Chikako Ragan, Sebastian Kurscheid, Eloisa Pagler, Hao Yang, Jeroen Krijgsveld5, Matthias W. Hentze, Thomas Preiss. Cell Reports. DOI:

Global changes of the RNA-bound proteome during the maternal-to-zygotic transition in Drosophila. Vasiliy O. Sysoev,    Bernd Fischer,    Christian K. Frese,    Ishaan Gupta,    Jeroen Krijgsveld,    Matthias W. Hentze,    Alfredo Castello   and Anne Ephrussi. Nature Communications DOI: 10.1038/ncomms12128

The new (dis)order in RNA regulation. Aino I. Järvelin, Marko Noerenberg, Ilan Davis and Alfredo Castello. Cell Communication and Signaling. DOI: 10.1007/978-1-4939-3067-8_8

  • 2014

A versatile assay for RNA-binding proteins in living cells. Strein, C., Allaeume, A.M., Hentze, M.W. and Castello, A. RNA 20 (5), 721-731.

  • 2013

The RNA-binding Protein Repertoire of Embryonic Stem Cells. Kwon, C., Hyerim, Y., Eichelbaum, K., Föhr, S., Fischer, B., You, K.T., Castello, A., Krijgsveld, J., Hentze, M.W. and Kim, N. Nat. Str. Mol. Biology. 2013 Aug 4.

RNA-Binding Proteins in Mendelian Disease and Cancer. Castello, A., Fischer, B., Hentze, M.W. and Preiss, T. Trends in Genetics 2013 Feb 14.

System-wide identification and activity landscape mapping of RNA-binding proteins by interactome capture. Castello, A., Strein, C., Horos, R., Beckmann, B., Hentze, M. Nature Protocols. 2013 Feb 14;8(3):491-500

  • 2012

Insights into RNA biology from a mammalian cell mRNA interactome. Castello, A. , Fischer, B., Schuschke, K., Horos, R., Beckmann, B.M., Strein, C., Humphreys, D.T., Preiss, T., Steinmetz, L.M., Krijgsveld, J. and Hentze, M.W. Cell. 2012 Jun 8;149(6):1393-406.

  • 2009

RNA nuclear export is blocked by poliovirus 2A protease and is concomitant with nucleoporin cleavage. Castello, A., Izquierdo, J.M., Welnowska, E. & Carrasco, L. J Cell Sci. 2009 Oct 15;122(Pt 20):3799-809.

Regulation of host translational machinery by african Swine Fever virus. Castello, A., Quintas, A., Sanchez, E.G., Sabina, P., Nogal, M., Carrasco, L. & Revilla, Y. PLoS Pathogens. 2009 Aug;5(8):e1000562.