RNA2017 – Prague

We are back from the RNA2107 in Prague. Very exciting talks!

One highlight, Adrian Krainer talked about SPINRAZA, a new therapy against spinal muscular atrophy (SMA) based on antisense oligos. SMA produces the loss of motor neurons that ends up in muscle wasting and early dead (the life expectation of a new born baby with type 1 SMA is ten months). The recently developed treatment treatment has shown excellent results in phase III clinical trials. Adrian guided us through the conception and development of the drug and included emotive videos of how SPINRAZA improves the life of children affected with SMA. An inspiring talk that demonstrates that basic science is fundamental for advancing applied research.

 

In their memory

With incredible sadness I received the terrible news that my colleagues and friends, Bernd Fischer and Katrin Eichelbaum, passed away. Bernd, Katrin and I formed a highly interdisciplinary team working from 2009 to 2014 at EMBL in Heidelberg. Bernd and I continued our close collaboration as independent group leaders. Together with other colleagues at EMBL, we achieved a long-standing challenge: the determination of the “near complete” atlas of human RNA-binding proteins. Katrin and Bernd were outstanding scientists and great friends.

I can only be grateful for having the opportunity to work with you. You are terribly missed.

Alfredo

Bernd Fischer

Katrin Eichelbaum

 

 

Celebrating our great success!

Explaining me why ENSEMBL IDs?

Postdoctoral position in RNA biology and Genomics in the Pelechano lab

Our collaborators in the Pelechano lab (Karolinska Institutet) are seeking for a postdoctoral fellow in RNA biology and genomics. The available postdoctoral position concerns developing and applying novel genomic approaches to study non-genetic heterogeneity in clonal population of cells. The candidate will focus on the study of translation regulation and its contribution to cell-to-cell variability in S. cerevisiae, with a special focus on ribosome dynamics, tRNA biology and post-transcriptional regulation. In a second stage the candidate will expand his/her work to the study of human cells. The candidate will perform original research in genomics, and acquire the required experimental and computational skills necessary for the completion of the project.

For the full information about this post visit the original job offer.

Postdoctoral position in Tim Nott’s lab

Our colleague Tim Nott offers a Wellcome Trust-funded postdoc position. The primary aim of the project is to understand the molecular basis and biochemical consequences of membraneless compartmentalisation in cells. The work will combine established methods of reconstituting membraneless organelles with the development of new biochemical assays and advanced microscopic imaging strategies.

Details of the post and how to apply can be found here:

https://www.recruit.ox.ac.uk/pls/hrisliverecruit/erq_jobspec_details_form.jobspec?p_id=127299

The closing date for applications is 22 February 2017.