Postdoctoral Position in Hematology, RNA Biology and Iron Metabolism

The Lab of Dr Mayka Sanchez at IJC (Barcelona) is looking for an enthusiastic postdoctoral candidate, who wants to work in a young and efficient team to address new and challenging aspects of haematology, RNA Biology and iron metabolism. The selected candidate will apply for salary funds from Generalitat Catalunya for a postdoctoral position.

Selection criteria

– Compulsory: Promising track record of early achievements, including significant publications (as main author, impact factor >6) in major international peer reviewed scientific journals.
– International mobility will be a plus.
– Proven Laboratory experience especially in haematology, microscopy, RNA Biology, mouse work, and/or iron biology.
– Good communication skills
– Languages: English (required), Spanish (helpful).

Conditions

– 3-year postdoctoral contract. Additional expenses connected to the project are provided.
– Starting: From January 2017

How to apply
Please send your application to msanchez@carrerasresearch.org before 28th October 2016. Please include:
– Subject of email: Candidate Postdoc-2016
– A CV including your contact details and it is compulsory to include your publications and Impact Factor and provide detailed information concerning fulfilling of criteria
– Names of two referees (with email and phone number)

Joining our lab

We are always seeking for talented and motivated postdocs, graduate and master students.

20160523_131432Postdoctoral associates

Fully funded postdoctoral positions (if any) are advertised here and at the Biochemistry website.  If none is available, we are happy to advise outstanding candidates in their applications to postdoctoral fellowships. To be successful in such applications, the candidate should have an excellent track record, including publications in peer-reviewed journal as first authors. Fellowships available include Marie Sklodowska-Curie, EMBO long-term fellowship, Newton International Fellowship and Sir Henry Wellcome Postdoctoral Fellowship. Fellowships from the candidate’s country are also an option to explore.

DPhil/PhD students

The Department of Biochemistry and the University of Oxford offer highly competitive and prestigious scholarships to carry out a DPhil (PhD) in one of the most vibrant scientific environments in the world. These scholarships are given through DPhil programmes that are grouped based on research focus and interests (more information here). Our laboratory is associated  to (and thus eligible from) three DPhil programmes: Biochemistry, DTP BBSRC and WT Chromosome & Developmental Biology. Students with strong CV are encouraged to apply. Selection process takes into consideration bachelor and/or master grades as well as previous research experience.

Master students

The Department of Biochemistry also offers a prestigious master programme, referred to as master by research. This 2-year programmes does not include scholarship and thus students should either be self-funded or should obtain a scholarship from other source. We expect the student to have excellent bachelor grades and some lab experience.

Don’t hesitate to contact us (alfredo.castellopalomares@bioch.ox.ac.uk) for more information.

Postdoctoral position in RNA biology and metabolism – DKFZ Heidelberg

The German Cancer Research Center (DKFZ) invites application for a highly motivated and creative postdoctoral researcher to explore the molecular bases of metabolic and genetic regulations. The DKFZ is located in the picturesque city of Heidelberg in the South of Germany and benefits from an exceptionally strong research environment, with Germany’s oldest university and several other leading life science research institutions in Europe.  The  successful  candidate  will  join  the  lab  of  Dr.  Bruno  Galy  in  the  „virus-­‐ associated carcinogenesis unit“.

Metabolic remodeling is emerging as a key process of physiology and disease. Although posttranscriptional regulations play a key role in shaping proteomes, genetic control of metabolism has so far been mostly investigated at the level of transcription. The interconnection between metabolism and the complex life of a mRNA, from its synthesis to its translation and decay, thus remains poorly understood. Iron metabolism is ideally suited   to   study   the   posttranscriptional   regulation   of   metabolism.   Indeed,   iron homeostasis is maintained by two RNA binding factors called Iron Regulatory Proteins (IRPs), which modulate the translation or turnover of target mRNAs. In this postdoctoral project, we will use high-­‐throughput technologies developed recently to define the regulatory scope of the IRP network on a system wide scale. This integrative approach will be carried out in vivo, using state-­‐of-­‐the-­‐art  IRP mouse models. With this work we wish to unveil new facets of a central homeostatic circuit in the cell, and constitute a basis for the study of other gene regulatory networks with similar properties.

The applicant holds a Ph.D. (or equivalent degree) in biology, biochemistry or related field  and  an  excellent  publication  record.  He/She  is  expected  to  have  a  strong background  in  RNA  biology.  A  solid  experience  with  cell  and  molecular  biology techniques and in particular high throughput approaches will be essential; familiarity with standard bioinformatical analysis of large data sets is also required. The candidate is rigorous, able to conduct independent research, but also enjoys interacting with colleagues of different disciplines and nations. Good presentation skills and experience on project management (importance of scheduling, deliverables, reporting) will be highly valued.

Funding for a total of 3 years is available and the position is open immediately. Your application (in English language) must include a CV, a summary of academic records, your research interests, and at least two letters of recommendation (or contact details of potential referees). For further question, please contact Dr. Bruno Galy (b.galy@dkfz.de).

PhD Student in the area of cancer metabolism – Galy lab, DKFZ, Heidelberg

The German Cancer Research Center (DKFZ) in Heidelberg, Germany, invites application for a highly motivated and creative PhD student to explore the molecular bases underlying metabolic reprogramming in cancer.

Cancer cells display profound metabolic alterations that enable them to meet the metabolic needs required for various aspects of malignancy. Understanding this metabolic remodeling is essential to decipher the fundamental mechanisms of tumorgenesis, as well as to find novel therapeutic solutions. Iron is a trace element important for many cellular functions and like other metabolic pathways, iron homeostatic mechanisms are frequently altered in cancer (Torti and Torti, Nat. Rev. Cancer, 2013).

In this project, we will make use of state-of-the-art tumor mouse models together with organoid cultures and various cell and molecular biology approaches to investigate the role of central regulatory networks of iron homeostasis in tumor biology, with a particular interest for intestinal cancers.

Profile

Applicants should hold a masters’ degree (or equivalent) in biology, biochemistry or related field, with an excellent background in tumor biology and a strong experience in cell and molecular biology techniques; experience in mouse models would be advantageous. The student shall be committed, enthusiastic, rigorous and goal oriented. The candidate shall be very well organized, have excellent communication and writing skills, and be able to work both independently and in a team environment.

Please send your CV, copies of certificates, transcript of records from Bachelor’s and Master’s studies, your research interests and contact addresses of two referees.

ADDITIONAL INFORMATION

http://www.dkfz.de/en/stellenangebote/index.php?id=090/2016