Post-doctoral position at DKFZ, Heidelberg

Here it is a job offer in the lab of an excellent scientist, collaborator and friend. For more information refeer to Dr. Bruno Galy: b.galy@Dkfz-Heidelberg.de

Job topic: Virus-Associated Carcinogenesis

The lab: The German Cancer Research Center (DKFZ) in Heidelberg, Germany, invites application for a highly motivated and creative postdoctoral researcher to explore the molecular bases underlying metabolic and genetic reprogramming in infection/inflammation-induced cancer. The DKFZ is located in the picturesque city of Heidelberg in the South of Germany and benefits from an exceptionally strong research
environment, with Germany’s oldest university and several other leading life science research institutions in Europe.
The successful candidate will join the newly created research group “Metabolism of infection/inflammation-induced cancer” (head: Dr. Bruno GALY) in the “virus-associated carcinogenesis” department of the DKFZ. One major focus of the lab is on iron metabolism, whose alterations are emerging as a key metabolic hallmark of cancer. Using a combination of biochemical and molecular biology assays together with state-of-the-art cellular and mouse models, the candidate will investigate the function of central regulatory networks of iron homeostasis in various aspects of tumor formation and progression.

The profile: The ideal candidate has a strong background in tumor biology and an excellent publication record. A solid experience with cell and molecular biology techniques and mouse models will be essential. Further experience with metabolic phenotyping and large-scale data analysis will be a strong plus. The applicant holds a Ph.D. (or equivalent degree) in biology, biochemistry or related field. She/He is rigorous, able to conduct independent research, has a strong team player attitude and is willing to advise junior staff.

New angles in the RNA field

In the last issue of the Biochemist (the journal of the Biochemical society) is focus on RNA.  The different reviews, written by leading RNA scientists, give an overview of the function of ribozymes, novel initiation codons and RNA modifications in RNA biology. In addition, this issue provides an comprehensive description of the mechanisms of RNA silencing in plants, the emergent roles of mitochondrial RNAs and chromosome silencing by Xist non-coding RNA. We have contributed to it with a snapshot in our current knowledge in RNA-binding proteins and the news avenues of research that aroused from the HeLa and HEK293 mRNA interactomes (Castello et al., Cell 2012 and Baltz et al., Mol Cell, 2012).

For more information visit: http://www.biochemist.org/bio/